loop (high ceiling)diuretics
ex;frusamide (lasix)-torasemide-bumetamide-ethacrynic acid (edecrine)
mode of action:inhibition Na reabsorption in ascending loop of henel and increase secretion K in distal tubule.
used in acute pulmonary odema.
note:very potent when given I/V,large dose results in hyponatremia(decrease Na in blood ),dehydration ,hypokalemia(decrease K in blood).
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